Detailed introduction

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About this resource

An Indian analytical study validating a quality-control method for harmine, harmaline, vasicine and vasicinone; the abstract calls the seed a reputed drug of Indian systems of medicine.

Pulpati H, Biradar YS, Rajani M. Journal of AOAC International. 2008;91(5):1179-1185.

Evidence or source type

This page identifies the material as the following source type: Analytical quality-control study. Whole plants, extracts, isolated compounds, laboratory studies and human studies carry different evidential meanings.

An independently written introduction based on the source's bibliographic record and abstract, separating source type, principal content and limitations. It is not a full-text translation.

What it contributes

Its principal contribution to this collection is summarized below.

An Indian analytical study validating a quality-control method for harmine, harmaline, vasicine and vasicinone; the abstract calls the seed a reputed drug of Indian systems of medicine.

Limitations

The following limitation should be read before interpreting the source.

“Indian systems of medicine” is an umbrella term and does not prove inclusion in classical Ayurvedic canon; this is not a clinical study.

Safety and interpretation

Syrian rue contains beta-carboline alkaloids, and the collection includes research on MAO activity, drug-metabolizing enzymes and poisoning reports. Laboratory activity and records of traditional use do not establish clinical efficacy or general safety in humans. Drug interactions, neurological, gastrointestinal and cardiovascular signs, and variation among preparations require separate evaluation. This page provides neither instructions for use nor diagnosis or treatment advice.

Ayurveda / Soma context

The abstract's phrase “Indian systems of medicine” is an umbrella term that may include several systems. It does not by itself establish a place in classical Ayurvedic canon.

Original source and reuse

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High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala ↗